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Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model

The ghrelin system has received substantial recognition as a potential target for novel anti-seizure drugs. Ghrelin receptor (ghrelin-R) signaling is complex, involving Gα(q/11), Gα(i/o), Gα(12/13), and β-arrestin pathways. In this study, we aimed to deepen our understanding regarding signaling path...

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Detalles Bibliográficos
Autores principales: Buckinx, An, Van Den Herrewegen, Yana, Pierre, Anouk, Cottone, Eleonora, Ben Haj Salah, Khoubaib, Fehrentz, Jean-Alain, Kooijman, Ron, De Bundel, Dimitri, Smolders, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567032/
https://www.ncbi.nlm.nih.gov/pubmed/31137460
http://dx.doi.org/10.3390/ijms20102480