Bone Metastasis Phenotype and Growth Undergo Regulation by Micro-Environment Stimuli: Efficacy of Early Therapy with HGF or TGFβ1-Type I Receptor Blockade

Hepatocyte growth factor (HGF) and transforming growth factor β1 (TGFβ1) are biological stimuli of the micro-environment which affect bone metastasis phenotype through transcription factors, but their influence on the growth is scarcely known. In a xenograft model prepared with 1833 bone metastatic...

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Detalles Bibliográficos
Autores principales: Bendinelli, Paola, Maroni, Paola, Dall’Olio, Valentina, Matteucci, Emanuela, Desiderio, Maria Alfonsina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567054/
https://www.ncbi.nlm.nih.gov/pubmed/31121879
http://dx.doi.org/10.3390/ijms20102520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567054/
https://www.ncbi.nlm.nih.gov/pubmed/31121879
http://dx.doi.org/10.3390/ijms20102520

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