Fibroblast Growth Factor 21 Stimulates Pancreatic Islet Autophagy via Inhibition of AMPK-mTOR Signaling

Background: Islet autophagy plays a role in glucose/lipid metabolism in type 2 diabetes mellitus. Meanwhile, fibroblast growth factor 21 (FGF21) has been found to regulate insulin sensitivity and glucose homeostasis. Whether FGF21 induces islet autophagy, remains to be elucidated. This study aimed t...

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Detalles Bibliográficos
Autores principales: Cheng, Sam Tsz Wai, Li, Stephen Yu Ting, Leung, Po Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567208/
https://www.ncbi.nlm.nih.gov/pubmed/31121855
http://dx.doi.org/10.3390/ijms20102517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567208/
https://www.ncbi.nlm.nih.gov/pubmed/31121855
http://dx.doi.org/10.3390/ijms20102517

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