Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity

Human hepatoma HepaRG cells express most drug metabolizing enzymes and constitute a pertinent in vitro alternative cell system to primary cultures of human hepatocytes in order to determine drug metabolism and evaluate the toxicity of xenobiotics. In this work, we established novel transgenic HepaRG...

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Detalles Bibliográficos
Autores principales: Vlach, Manuel, Quesnot, Nicolas, Dubois-Pot-Schneider, Hélène, Ribault, Catherine, Verres, Yann, Petitjean, Kilian, Rauch, Claudine, Morel, Fabrice, Robin, Marie-Anne, Corlu, Anne, Loyer, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567340/
https://www.ncbi.nlm.nih.gov/pubmed/31096615
http://dx.doi.org/10.3390/s19102245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567340/
https://www.ncbi.nlm.nih.gov/pubmed/31096615
http://dx.doi.org/10.3390/s19102245

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