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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
For the transmissible, neurogenerative family of prion diseases, few human models of infection exist and none represent structured neuronal tissue. Human cerebral organoids are self-organizing, three-dimensional brain tissues that can be grown from induced pluripotent stem cells. Organoids can model...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567389/ https://www.ncbi.nlm.nih.gov/pubmed/31196223 http://dx.doi.org/10.1186/s40478-019-0742-2 |