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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

For the transmissible, neurogenerative family of prion diseases, few human models of infection exist and none represent structured neuronal tissue. Human cerebral organoids are self-organizing, three-dimensional brain tissues that can be grown from induced pluripotent stem cells. Organoids can model...

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Detalles Bibliográficos
Autores principales:	Groveman, Bradley R., Foliaki, Simote T., Orru, Christina D., Zanusso, Gianluigi, Carroll, James A., Race, Brent, Haigh, Cathryn L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567389/ https://www.ncbi.nlm.nih.gov/pubmed/31196223 http://dx.doi.org/10.1186/s40478-019-0742-2

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