Loss of endosomal recycling factor RAB11 coupled with complex regulation of MAPK/ERK/AKT signaling in postmortem spinal cord specimens of sporadic amyotrophic lateral sclerosis patients

Synaptic abnormalities, perturbed endosomal recycling mediated by loss of the small GTPase RAB11, and neuroinflammatory signaling have been associated with multiple neurodegenerative diseases including the motor neuron disease, amyotrophic lateral sclerosis (ALS). This is consistent with the neuropr...

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Detalles Bibliográficos
Autores principales: Mitra, Joy, Hegde, Pavana M., Hegde, Muralidhar L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567394/
https://www.ncbi.nlm.nih.gov/pubmed/31196199
http://dx.doi.org/10.1186/s13041-019-0475-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567394/
https://www.ncbi.nlm.nih.gov/pubmed/31196199
http://dx.doi.org/10.1186/s13041-019-0475-y

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