Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects

BACKGROUND: Clinically, for stem cell-based therapy (SCBT), autologous stem cells are considered better than allogenic stem cells because of little immune rejection and no risk of communicable disease infection. However, severe maxillofacial bone defects restoration needs sufficient autologous stem...

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Detalles Bibliográficos
Autores principales: Shi, Anyuan, Heinayati, Aerali, Bao, Dongyu, Liu, Huifen, Ding, Xiaochen, Tong, Xin, Wang, Liudi, Wang, Bin, Qin, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567469/
https://www.ncbi.nlm.nih.gov/pubmed/31196174
http://dx.doi.org/10.1186/s13287-019-1281-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567469/
https://www.ncbi.nlm.nih.gov/pubmed/31196174
http://dx.doi.org/10.1186/s13287-019-1281-2

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