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Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects
BACKGROUND: Clinically, for stem cell-based therapy (SCBT), autologous stem cells are considered better than allogenic stem cells because of little immune rejection and no risk of communicable disease infection. However, severe maxillofacial bone defects restoration needs sufficient autologous stem...
Autores principales: | Shi, Anyuan, Heinayati, Aerali, Bao, Dongyu, Liu, Huifen, Ding, Xiaochen, Tong, Xin, Wang, Liudi, Wang, Bin, Qin, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567469/ https://www.ncbi.nlm.nih.gov/pubmed/31196174 http://dx.doi.org/10.1186/s13287-019-1281-2 |
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