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Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAs

BACKGROUND: Exosomes derived from dental pulp stem cells (DPSCs) can be used as biomimetic tools to induce odontogenic differentiation of stem cells, but the regulatory mechanisms and functions of exosome-encapsulated microRNAs are still unknown. The present study aimed to clarify the role of microR...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoli, Zhong, Yingqun, Kong, Yuanyuan, Chen, Yanan, Feng, Junming, Zheng, Jianmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567518/
https://www.ncbi.nlm.nih.gov/pubmed/31196201
http://dx.doi.org/10.1186/s13287-019-1278-x