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SIRT7 regulates hepatocellular carcinoma response to therapy by altering the p53-dependent cell death pathway
BACKGROUND: Optimal therapeutic strategies for hepatocellular carcinoma (HCC) patients are still challenging due to the high recurrence rate after surgical resection and chemotherapy resistance. Growing evidence shows that genetic and epigenetic alterations are involved in HCC progression and resist...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567523/ https://www.ncbi.nlm.nih.gov/pubmed/31196136 http://dx.doi.org/10.1186/s13046-019-1246-4 |