SIRT7 regulates hepatocellular carcinoma response to therapy by altering the p53-dependent cell death pathway

BACKGROUND: Optimal therapeutic strategies for hepatocellular carcinoma (HCC) patients are still challenging due to the high recurrence rate after surgical resection and chemotherapy resistance. Growing evidence shows that genetic and epigenetic alterations are involved in HCC progression and resist...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Wozniak, Ann, Adams, Abby, Cox, Josiah, Vittal, Anusha, Voss, Jordan, Bridges, Brian, Weinman, Steven A., Li, Zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567523/
https://www.ncbi.nlm.nih.gov/pubmed/31196136
http://dx.doi.org/10.1186/s13046-019-1246-4

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