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IgG Galactosylation status combined with MYOM2-rs2294066 precisely predicts anti-TNF response in ankylosing spondylitis

BACKGROUND: Tumor necrosis factor (TNF) blockers have a high efficacy in treating Ankylosing Spondylitis (AS), yet up to 40% of AS patients show poor or even no response to this treatment. In this paper, we aim to build an approach to predict the response prior to clinical treatment. METHODS: AS pat...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Zhu, Qi, Han, Jing, Zhang, Hui, Li, Yuan, Ma, Yanyun, He, Dongyi, Gu, Jianxin, Zhou, Xiaodong, Reveille, John D., Jin, Li, Zou, Hejian, Ren, Shifang, Wang, Jiucun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567531/
https://www.ncbi.nlm.nih.gov/pubmed/31195969
http://dx.doi.org/10.1186/s10020-019-0093-2