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Telomere length is greater in ALS than in controls: a whole genome sequencing study

Background: Amyotrophic lateral sclerosis is a neurodegenerative disease of motor neurons resulting in progressive paralysis and death, typically within 3–5 years. Although the heritability of ALS is about 60%, only about 11% is explained by common gene variants, suggesting that other forms of genet...

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Detalles Bibliográficos
Autores principales: Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Fang, Ton, Sproviero, William, Jones, Ashley R., Opie-Martin, Sarah, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Powell, John F., Dobson, Richard, Newhouse, Steven J., Al-Chalabi, Ammar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567548/
https://www.ncbi.nlm.nih.gov/pubmed/30931641
http://dx.doi.org/10.1080/21678421.2019.1586951