DNA damage-induced activation of ATM promotes β-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells

BACKGROUND: AT-rich interactive domain-containing protein 1A (ARID1A) is a subunit of the mammary SWI/SNF chromatin remodeling complex and a tumor suppressor protein. The loss of ARID1A been observed in several types of human cancers and associated with poor patient prognosis. Previously, we have re...

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Detalles Bibliográficos
Autores principales: Jiang, Zhou-hua, Peng, Tao, Qian, Hai-long, Lu, Cai-de, Qiu, Feng, Zhang, Su-zhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567580/
https://www.ncbi.nlm.nih.gov/pubmed/31210753
http://dx.doi.org/10.1186/s12935-019-0878-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567580/
https://www.ncbi.nlm.nih.gov/pubmed/31210753
http://dx.doi.org/10.1186/s12935-019-0878-y

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