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DNA damage-induced activation of ATM promotes β-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells

BACKGROUND: AT-rich interactive domain-containing protein 1A (ARID1A) is a subunit of the mammary SWI/SNF chromatin remodeling complex and a tumor suppressor protein. The loss of ARID1A been observed in several types of human cancers and associated with poor patient prognosis. Previously, we have re...

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Detalles Bibliográficos
Autores principales:	Jiang, Zhou-hua, Peng, Tao, Qian, Hai-long, Lu, Cai-de, Qiu, Feng, Zhang, Su-zhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567580/ https://www.ncbi.nlm.nih.gov/pubmed/31210753 http://dx.doi.org/10.1186/s12935-019-0878-y

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