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Colorectal cancer-derived extracellular vesicles induce transformation of fibroblasts into colon carcinoma cells

BACKGROUND: We reported that horizontal transfer of malignant traits to target cells is a potential pathway to explain cancer dissemination. Although these results were encouraging, they were never corroborated by data showing the molecular mechanisms responsible for the observed phenomenon. METHODS...

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Detalles Bibliográficos
Autores principales: Abdouh, Mohamed, Floris, Matteo, Gao, Zu-Hua, Arena, Vincenzo, Arena, Manuel, Arena, Goffredo Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567673/
https://www.ncbi.nlm.nih.gov/pubmed/31200749
http://dx.doi.org/10.1186/s13046-019-1248-2