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Dexmedetomidine improves cognition after carotid endarterectomy by inhibiting cerebral inflammation and enhancing brain-derived neurotrophic factor expression

OBJECTIVES: Carotid endarterectomy (CEA) is efficient in preventing stroke for patients with significant carotid stenosis, but results in mild cognitive dysfunction. Dexmedetomidine is neuroprotective in stroke models. We hypothesized that dexmedetomidine may improve cognition after CEA. METHODS: Fo...

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Detalles Bibliográficos
Autores principales: Ge, Yali, Li, Qian, Nie, Yuyan, Gao, Ju, Luo, Ke, Fang, Xiangzhi, Wang, Cunjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567697/
https://www.ncbi.nlm.nih.gov/pubmed/31014147
http://dx.doi.org/10.1177/0300060519843738