Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life

Rationale: The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. However, whether and how GDM exposure induces fetal programming of adult cardiac dysfunctional phenotype, especially the underlying epigenetic molecular mechanisms and theranostics remain unclear. To address thi...

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Detalles Bibliográficos
Autores principales: Chen, Zewen, Gong, Lei, Zhang, Peng, Li, Yong, Liu, Bailin, Zhang, Lubo, Zhuang, Jian, Xiao, Daliao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567811/
https://www.ncbi.nlm.nih.gov/pubmed/31223283
http://dx.doi.org/10.7150/ijbs.33044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567811/
https://www.ncbi.nlm.nih.gov/pubmed/31223283
http://dx.doi.org/10.7150/ijbs.33044

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