miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a common hepatic disease with an increasing prevalence but an unclear aetiology. This study aimed to investigate the functional implications of microRNA-122 (miR-122) in the pathogenesis of NAFLD and the possible molecular mechanisms. METHODS:...

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Detalles Bibliográficos
Autores principales: Long, Jun-Ke, Dai, Wen, Zheng, Ya-Wen, Zhao, Shui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567918/
https://www.ncbi.nlm.nih.gov/pubmed/31195981
http://dx.doi.org/10.1186/s10020-019-0085-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567918/
https://www.ncbi.nlm.nih.gov/pubmed/31195981
http://dx.doi.org/10.1186/s10020-019-0085-2

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