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Combined low-dose LiCl and LY294002 for the treatment of osteoporosis in ovariectomized rats
BACKGROUND: To provide a low-toxicity and high-efficacy clinical treatment for osteoporosis via a novel combination of LiCl and LY294002. METHODS: The protein levels of p-AKT, AKT, p-GSK3β, GSK3β, β-catenin, p-β-catenin, and NFATC1 were measured in osteoblasts and osteoclasts by Western blot. ALP ac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567919/ https://www.ncbi.nlm.nih.gov/pubmed/31196133 http://dx.doi.org/10.1186/s13018-019-1210-1 |