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Lgr5-mediated p53 Repression through PDCD5 leads to doxorubicin resistance in Hepatocellular Carcinoma

The devastating prognosis of hepatocellular carcinoma (HCC) is partially attributed to chemotherapy resistance. Accumulating evidence suggests that the epithelial-mesenchymal transition (EMT) is a key driving force of carcinoma metastasis and chemoresistance in solid tumors. Leucine-rich repeat-cont...

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Detalles Bibliográficos
Autores principales: Ma, Zhili, Guo, Deliang, Wang, Quanxiong, Liu, Pengpeng, Xiao, Yushao, Wu, Ping, Wang, Yitao, Chen, Baiyang, Liu, Zhisu, Liu, Quanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568175/
https://www.ncbi.nlm.nih.gov/pubmed/31244936
http://dx.doi.org/10.7150/thno.30562