The cell-penetrating FOXM1 N-terminus (M1-138) demonstrates potent inhibitory effects on cancer cells by targeting FOXM1 and FOXM1-interacting factor SMAD3

Transcription factor FOXM1 is involved in stimulating cell proliferation, enhancing DNA damage repair, promoting metastasis of cancer cells, and the inhibition of FOXM1 has been shown to prevent the initiation and progression of multiple cancers and FOXM1 is considered to be an effective target for...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenwang, Bu, Huitong, Yu, Jingwei, Chen, Yan, Pei, Chaozhu, Yu, Li, Huang, Xiaoqin, Tan, Guixiang, Tan, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568178/
https://www.ncbi.nlm.nih.gov/pubmed/31244930
http://dx.doi.org/10.7150/thno.32693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568178/
https://www.ncbi.nlm.nih.gov/pubmed/31244930
http://dx.doi.org/10.7150/thno.32693

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