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CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages

Rationale: Bone is one of the most common metastatic sites of breast cancer. CD137 (4-1BB), a member of the tumor necrosis factor (TNF) receptor superfamily, is mainly expressed in activated leukocytes. Previous study demonstrates the effect of CD137-CD137L bidirectional signaling pathway on RANKL-m...

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Detalles Bibliográficos
Autores principales: Jiang, Pengling, Gao, Wenjuan, Ma, Tiansi, Wang, Rongrong, Piao, Yongjun, Dong, Xiaoli, Wang, Peng, Zhang, Xuehui, Liu, Yanhua, Su, Weijun, Xiang, Rong, Zhang, Jin, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568184/
https://www.ncbi.nlm.nih.gov/pubmed/31244935
http://dx.doi.org/10.7150/thno.29617