Continuous nonenzymatic cross-replication of DNA strands with in situ activated DNA oligonucleotides

Continuous enzyme-free replication of oligonucleotides is central for open-ended evolution experiments that mimic the origin of life. Here, we studied a reaction system, whereby two 24mer DNA templates cross-catalyzed each other's synthesis from four 12mer DNA fragments, two of which were in si...

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Detalles Bibliográficos
Autores principales: Edeleva, Evgeniia, Salditt, Annalena, Stamp, Julian, Schwintek, Philipp, Boekhoven, Job, Braun, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568275/
https://www.ncbi.nlm.nih.gov/pubmed/31293769
http://dx.doi.org/10.1039/c9sc00770a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568275/
https://www.ncbi.nlm.nih.gov/pubmed/31293769
http://dx.doi.org/10.1039/c9sc00770a

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