Cargando…

Zn(OTf)(2)-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds

Intramolecular hydroarylations of N-propargylated tetrahydrocarbolines were efficiently mediated using a unique combination of Zn(OTf)(2) with t-BuOH under neutral conditions. Use of the artificial force induced reaction method in the global reaction route mapping strategy provided insights into the...

Descripción completa

Detalles Bibliográficos
Autores principales: Yorimoto, Sadaiwa, Tsubouchi, Akira, Mizoguchi, Haruki, Oikawa, Hideaki, Tsunekawa, Yoshiaki, Ichino, Tomoya, Maeda, Satoshi, Oguri, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568280/
https://www.ncbi.nlm.nih.gov/pubmed/31293753
http://dx.doi.org/10.1039/c9sc01507h