Cargando…

Zn(OTf)(2)-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds

Intramolecular hydroarylations of N-propargylated tetrahydrocarbolines were efficiently mediated using a unique combination of Zn(OTf)(2) with t-BuOH under neutral conditions. Use of the artificial force induced reaction method in the global reaction route mapping strategy provided insights into the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yorimoto, Sadaiwa, Tsubouchi, Akira, Mizoguchi, Haruki, Oikawa, Hideaki, Tsunekawa, Yoshiaki, Ichino, Tomoya, Maeda, Satoshi, Oguri, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568280/ https://www.ncbi.nlm.nih.gov/pubmed/31293753 http://dx.doi.org/10.1039/c9sc01507h

Ejemplares similares

Parallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization
por: Oguri, Hiroki, et al.
Publicado: (2012)

Site-selective C–H activation and regiospecific annulation using propargylic carbonates
por: Lu, Qingquan, et al.
Publicado: (2019)

Concise and Efficient Synthesis of Indole–Indolone Scaffolds through MeOTf-Induced Annulation of N-(2-Cyanoaryl)indoles
por: Zou, Song, et al.
Publicado: (2019)

Sc(OTf)(3)-Mediated [4 + 2] Annulations of N-Carbonyl Aryldiazenes with Cyclopentadiene to Construct Cinnoline Derivatives: Azo-Povarov Reaction
por: Jiménez-Aberásturi, Xabier, et al.
Publicado: (2022)

1-Methyl-1,2,3,4-tetrahydrocarbolin-2-ium-3-carboxylate
por: Lu, Cheng-Tao, et al.
Publicado: (2010)

Solvent-Dependent Divergent Functions of Sc(OTf)(3) in Stereoselective Epoxide-Opening Spiroketalizations
por: Sharma, Indrajeet, et al.
Publicado: (2014)

Synthesis and Structural Verification of an ArI(OTf)(2), NO(2)‐Ph‐I(OTf)(2)
por: Sharp‐Bucknall, Lachlan, et al.
Publicado: (2022)

Chicken Ovotransferrin Variants OTF(B) and OTF(C) Harboring Substitution of GAT (Asp) to AAT (Asn) in the Codon 500 and their Antimicrobial Activity
por: Kinoshita, Keiji, et al.
Publicado: (2016)

Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
por: Su, Ji, et al.
Publicado: (2015)

Rh-Catalyzed Cascade C-H Activation/Annulation of N-Hydroxybenzamides and Propargylic Acetates for Modular Access to Isoquinolones
por: Fang, Taibei, et al.
Publicado: (2022)

Annulative coupling of vinylboronic esters: aryne-triggered 1,2-metallate rearrangement
por: Mizoguchi, Haruki, et al.
Publicado: (2022)

Bi(OTf)(3) and SiO(2)-Bi(OTf)(3) as Effective Catalysts for the Ferrier Rearrangement#
por: Babu, J. Lokesh, et al.
Publicado: (2005)

Effect of Propargylic Substituents on Enantioselectivity and Reactivity in Ruthenium-Catalyzed Propargylic Substitution Reactions: A DFT Study
por: Sakata, Ken, et al.
Publicado: (2022)

Formal total synthesis of histrionicotoxin alkaloids via Hg(OTf)(2)-catalyzed cycloisomerization and SmI(2)-induced ring expansion
por: Matsumura, Kunihiro, et al.
Publicado: (2018)

Tropane and related alkaloid skeletons via a radical [3+3]-annulation process
por: Colson, Eloïse, et al.
Publicado: (2022)

Divergent Elementoboration: 1,3‐Haloboration versus 1,1‐Carboboration of Propargyl Esters
por: Wilkins, Lewis C., et al.
Publicado: (2018)

Cu-catalyzed, Mn-mediated propargylation and allenylation of aldehydes with propargyl bromides
por: Zhang, Rongli, et al.
Publicado: (2022)

Bi(OTf)(3)-catalysed intramolecular cyclisation of unsaturated acetals
por: Saget, Raphaël, et al.
Publicado: (2021)

A Comprehensive Experimental Emulation for OTFS Waveform RF-Impairments
por: Abushattal, Abdelrahman, et al.
Publicado: (2022)

A Transformer-Based Channel Estimation Method for OTFS Systems
por: Sun, Teng, et al.
Publicado: (2023)

Hamming Distance Optimized Underwater Acoustic OTFS-IM Systems
por: Guo, Xiaopeng, et al.
Publicado: (2023)

Rh(II)/Pd(0) Dual-Catalyzed Regio-Divergent Three-Component Propargylic Substitution
por: Xu, Jie, et al.
Publicado: (2023)

Triflimide-catalyzed allylsilane annulations of benzylic alcohols for the divergent synthesis of indanes and tetralins
por: Reddel, Jordan C. T., et al.
Publicado: (2017)

Divergent rhodium-catalyzed electrochemical vinylic C–H annulation of acrylamides with alkynes
por: Xing, Yi-Kang, et al.
Publicado: (2021)

A new approach for the synthesis of bisindoles through AgOTf as catalyst
por: Beltrá, Jorge, et al.
Publicado: (2014)

Electrocatalytic Water Oxidation with α-[Fe(mcp)(OTf)(2)] and Analogues
por: D’Agostini, Silvia, et al.
Publicado: (2021)

Superimposed Perfect Binary Array-Aided Channel Estimation for OTFS Systems
por: Tang, Zuping, et al.
Publicado: (2023)

Stereoselective Domino Rearrangement peri-Annulation of Cinchona Alkaloid Derivatives with 8-Bromo-1-naphthyl Grignard
por: Boratyński, Przemysław J.
Publicado: (2022)

Photoredox cobalt-catalyzed regio-, diastereo- and enantioselective propargylation of aldehydes via propargyl radicals
por: Wang, Lei, et al.
Publicado: (2023)

Underlying Security Transmission Design for Orthogonal Time Frequency Space (OTFS) Modulation
por: Liang, Wei, et al.
Publicado: (2022)

Copper-catalysed enantioselective intramolecular etherification of propargylic esters: synthetic approach to chiral isochromans
por: Liu, Shiyao, et al.
Publicado: (2019)

Establishing the concept of aza-[3 + 3] annulations using enones as a key expansion of this unified strategy in alkaloid synthesis
por: Gerasyuto, Aleksey I, et al.
Publicado: (2013)

Regioselective trans-Carboboration of Propargyl Alcohols
por: Jin, Hongming, et al.
Publicado: (2019)

Photoredox Propargylation of Aldehydes Catalytic in Titanium
por: Calogero, Francesco, et al.
Publicado: (2021)

Interplay of diruthenium catalyst in controlling enantioselective propargylic substitution reactions with visible light-generated alkyl radicals
por: Zhang, Yulin, et al.
Publicado: (2023)

Homogeneous Sc(OTf)(3)-Catalyzed Direct Allylation Reactions of General Alcohols with Allylsilanes
por: Di, Yuanjun, et al.
Publicado: (2018)

A three-component, Zn(OTf)(2)-mediated entry into trisubstituted 2-aminoimidazoles
por: Lukin, Alexei, et al.
Publicado: (2019)

Persistent Homology Approach for Human Presence Detection from 60 GHz OTFS Transmissions
por: Maršálek, Roman, et al.
Publicado: (2023)

Annulate lamellae: comparison of antigenic epitopes of annulate lamellae membranes with the nuclear envelope
Publicado: (1988)

Reversal of Enantioselectivity in the Conjugate Addition Reaction of Cyclic Enones with the CuOTf/Azolium Catalytic System
por: Nakano, Yuki, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tkel9d0didd2f88fqqpp7pg8b4