Cyano-borrowing reaction: nickel-catalyzed direct conversion of cyanohydrins and aldehydes/ketones to β-cyano ketone

A direct nickel-catalyzed, high atom- and step-economical reaction of cyanohydrins with aldehydes or ketones via an unprecedented “cyano-borrowing reaction” has been developed. Cleavage of the C–CN bond of cyanohydrins followed by aldol condensation and conjugate addition of cyanide to α,β-unsaturat...

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Detalles Bibliográficos
Autores principales: Li, Zhao-Feng, Li, Qian, Ren, Li-Qing, Li, Qing-Hua, Peng, Yun-Gui, Liu, Tang-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568282/
https://www.ncbi.nlm.nih.gov/pubmed/31293766
http://dx.doi.org/10.1039/c9sc00640k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568282/
https://www.ncbi.nlm.nih.gov/pubmed/31293766
http://dx.doi.org/10.1039/c9sc00640k

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