Cargando…
DMPK gene DNA methylation levels are associated with muscular and respiratory profiles in DM1
OBJECTIVE: To assess the effects of dystrophia myotonica protein kinase (DMPK) DNA methylation (DNAme) epivariation on muscular and respiratory profiles in patients with myotonic dystrophy type 1 (DM1). METHODS: Phenotypes were assessed with standardized measures. Pyrosequencing of bisulfite-treated...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568328/ https://www.ncbi.nlm.nih.gov/pubmed/31334355 http://dx.doi.org/10.1212/NXG.0000000000000338 |