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Medication-related osteonecrosis of the jaws after tooth extraction in senescent female mice treated with zoledronic acid: Microtomographic, histological and immunohistochemical characterization

Treatment with cumulative dosages of zoledronic acid (ZA) in elderly patients is a risk factor for the development of medication-related osteonecrosis of the jaws (MRONJ), mainly related to surgical triggers such as tooth extraction. However, animal models for the investigation and understanding of...

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Detalles Bibliográficos
Autores principales: Biguetti, Claudia Cristina, De Oliva, André Hergesel, Healy, Kent, Mahmoud, Ramez Hassan, Custódio, Isabela Do Carmo, Constantino, Dulce Helena, Ervolino, Edilson, Duarte, Marco Antonio Hungaro, Fakhouri, Walid D., Matsumoto, Mariza Akemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568384/
https://www.ncbi.nlm.nih.gov/pubmed/31199812
http://dx.doi.org/10.1371/journal.pone.0214173