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Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice

Type 1 diabetes (T1D) is a chronic multi-factorial disorder characterized by the immune-mediated destruction of insulin-producing pancreatic beta cells. Variations at a large number of genes influence susceptibility to spontaneous autoimmune T1D in non-obese diabetic (NOD) mice, one of the most freq...

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Detalles Bibliográficos
Autores principales: Mattner, Jochen, Mohammed, Javid P., Fusakio, Michael E., Giessler, Claudia, Hackstein, Carl-Philipp, Opoka, Robert, Wrage, Marius, Schey, Regina, Clark, Jan, Fraser, Heather I., Rainbow, Daniel B., Wicker, Linda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568395/
https://www.ncbi.nlm.nih.gov/pubmed/31199784
http://dx.doi.org/10.1371/journal.pgen.1008178