Cargando…
Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice
Type 1 diabetes (T1D) is a chronic multi-factorial disorder characterized by the immune-mediated destruction of insulin-producing pancreatic beta cells. Variations at a large number of genes influence susceptibility to spontaneous autoimmune T1D in non-obese diabetic (NOD) mice, one of the most freq...
Autores principales: | Mattner, Jochen, Mohammed, Javid P., Fusakio, Michael E., Giessler, Claudia, Hackstein, Carl-Philipp, Opoka, Robert, Wrage, Marius, Schey, Regina, Clark, Jan, Fraser, Heather I., Rainbow, Daniel B., Wicker, Linda S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568395/ https://www.ncbi.nlm.nih.gov/pubmed/31199784 http://dx.doi.org/10.1371/journal.pgen.1008178 |
Ejemplares similares
-
Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse
Publicado: (1987) -
The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice
por: Ansari, Mohammed Javeed I., et al.
Publicado: (2003) -
CD101 inhibits the expansion of colitogenic T cells
por: Schey, Regina, et al.
Publicado: (2016) -
Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice
por: Fraser, Heather I., et al.
Publicado: (2015) -
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
Publicado: (1996)