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Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury

BACKGROUND: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolem...

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Detalles Bibliográficos
Autores principales: Pluijmert, Niek J., den Haan, Melina C., van Zuylen, Vanessa L., Steendijk, Paul, de Boer, Hetty C., van Zonneveld, Anton J., Fibbe, Willem E., Schalij, Martin J., Quax, Paul H. A., Atsma, Douwe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570022/
https://www.ncbi.nlm.nih.gov/pubmed/31199833
http://dx.doi.org/10.1371/journal.pone.0217582