Cargando…
Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury
BACKGROUND: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolem...
Autores principales: | Pluijmert, Niek J., den Haan, Melina C., van Zuylen, Vanessa L., Steendijk, Paul, de Boer, Hetty C., van Zonneveld, Anton J., Fibbe, Willem E., Schalij, Martin J., Quax, Paul H. A., Atsma, Douwe E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570022/ https://www.ncbi.nlm.nih.gov/pubmed/31199833 http://dx.doi.org/10.1371/journal.pone.0217582 |
Ejemplares similares
-
Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice
por: Pluijmert, Niek J., et al.
Publicado: (2020) -
Discrepant Results of Experimental Human Mesenchymal Stromal Cell Therapy after Myocardial Infarction: Are Animal Models Robust Enough?
por: den Haan, Melina C., et al.
Publicado: (2016) -
Myocardial infarction models in NOD/Scid mice for cell therapy research: permanent ischemia vs ischemia–reperfusion
por: van Zuylen, Vanessa-Leigh, et al.
Publicado: (2015) -
Post-ischemic Myocardial Inflammatory Response: A Complex and Dynamic Process Susceptible to Immunomodulatory Therapies
por: Pluijmert, Niek J., et al.
Publicado: (2021) -
Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response
por: de Jong, Rob C. M., et al.
Publicado: (2018)