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Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage

Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci of prokaryotes are composed of 30-40 bp repeats separated by equally short sequences of plasmid and bacteriophage origin known as spacers(1–3). Spacers are transcribed and processed into short CRISPR RNAs (crRNAs) that are used...

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Detalles Bibliográficos
Autores principales: Meeske, Alexander J., Nakandakari-Higa, Sandra, Marraffini, Luciano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570424/
https://www.ncbi.nlm.nih.gov/pubmed/31142834
http://dx.doi.org/10.1038/s41586-019-1257-5