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Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage
Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci of prokaryotes are composed of 30-40 bp repeats separated by equally short sequences of plasmid and bacteriophage origin known as spacers(1–3). Spacers are transcribed and processed into short CRISPR RNAs (crRNAs) that are used...
Autores principales: | Meeske, Alexander J., Nakandakari-Higa, Sandra, Marraffini, Luciano A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570424/ https://www.ncbi.nlm.nih.gov/pubmed/31142834 http://dx.doi.org/10.1038/s41586-019-1257-5 |
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