Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall

Patient-derived xenografts (PDX) are generated in immune deficient mice and demonstrate histologic and molecular features similar to their corresponding human tumors. However, murine tumors (non-human) spontaneously occur in these models. 120 consecutive patients with high-risk primary breast cancer...

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Detalles Bibliográficos
Autores principales: Moyer, Ann M., Yu, Jia, Sinnwell, Jason P., Dockter, Travis J., Suman, Vera J., Weinshilboum, Richard M., Boughey, Judy C., Goetz, Matthew P., Visscher, Daniel W., Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570466/
https://www.ncbi.nlm.nih.gov/pubmed/31231469
http://dx.doi.org/10.18632/oncotarget.27001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570466/
https://www.ncbi.nlm.nih.gov/pubmed/31231469
http://dx.doi.org/10.18632/oncotarget.27001

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