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Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining

Estrogen-receptor negative (ERneg) breast cancer is an aggressive breast cancer subtype in the need for new therapeutic options. We have analyzed metabolomics, proteomics and transcriptomics data for a cohort of 276 breast tumors (MetaCancer study) and nine public transcriptomics datasets using univ...

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Detalles Bibliográficos
Autores principales: Barupal, Dinesh Kumar, Gao, Bei, Budczies, Jan, Phinney, Brett S., Perroud, Bertrand, Denkert, Carsten, Fiehn, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570467/
https://www.ncbi.nlm.nih.gov/pubmed/31231467
http://dx.doi.org/10.18632/oncotarget.26995