Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas

Germline mutations in the tumor suppressor Adenomatous Polyposis Coli (APC) define Familial Adenomatous Polyposis (FAP), the genetic predisposition to developing adenomatous polyps. Recent sequencing of FAP adenomas have challenged established dogma that APC mutations alone represent the adenoma mut...

Descripción completa

Detalles Bibliográficos
Autores principales: Delacruz, Richard Glenn C., Sandoval, Imelda T., Chang, Kyle, Miller, Braden N., Reyes-Uribe, Laura, Borras, Ester, Lynch, Patrick M., Taggart, Melissa W., Hawk, Ernest T., Vilar, Eduardo, Jones, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570471/
https://www.ncbi.nlm.nih.gov/pubmed/31231471
http://dx.doi.org/10.18632/oncotarget.27003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570471/
https://www.ncbi.nlm.nih.gov/pubmed/31231471
http://dx.doi.org/10.18632/oncotarget.27003

Ejemplares similares