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PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall
Centrioles play critical roles in organizing the assembly of the mitotic spindle and templating the formation of primary cilia. Centriole duplication occurs once per cell cycle and is regulated by Polo-like kinase 4 (PLK4). Although significant progress has been made in understanding centriole compo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570480/ https://www.ncbi.nlm.nih.gov/pubmed/31115335 http://dx.doi.org/10.7554/eLife.46054 |