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Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock

Maintenance of epigenetic modifiers is of utmost importance to preserve the epigenome and consequently appropriate cellular functioning. Here, we analyzed Polycomb group protein (PcG) complex integrity in response to heat shock (HS). Upon HS, various Polycomb Repressive Complex (PRC)1 and PRC2 subun...

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Detalles Bibliográficos
Autores principales: Azkanaz, Maria, Rodríguez López, Aida, de Boer, Bauke, Huiting, Wouter, Angrand, Pierre-Olivier, Vellenga, Edo, Kampinga, Harm H, Bergink, Steven, Martens, Joost HA, Schuringa, Jan Jacob, van den Boom, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570483/
https://www.ncbi.nlm.nih.gov/pubmed/31199242
http://dx.doi.org/10.7554/eLife.45205