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Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis

[Image: see text] The accurate and precise determination of binding interactions plays a central role in fields such as drug discovery where structure–activity relationships guide the selection and optimization of drug leads. Binding is often assessed by monitoring the response caused by varying one...

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Detalles Bibliográficos
Autor principal: Tonge, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570549/
https://www.ncbi.nlm.nih.gov/pubmed/30860805
http://dx.doi.org/10.1021/acsinfecdis.9b00012