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Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression

Suppressor of cytokine signaling-3 (SOCS3) is a negative regulator of actions of cytokines and the metabolic hormone leptin. In the hypothalamus, SOCS3 is induced in response to several conditions such as inflammation and high-fat diet feeding, modulates cellular signaling of cytokines and leptin, a...

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Detalles Bibliográficos
Autores principales: Cordonier, Elizabeth L, Liu, Tiemin, Saito, Kenji, Chen, Siyu S, Xu, Yong, Fukuda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570635/
https://www.ncbi.nlm.nih.gov/pubmed/31214662
http://dx.doi.org/10.1210/js.2019-00077