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Target attainment of cefotaxime in critically ill children with meningococcal septic shock as a model for cefotaxime dosing in severe pediatric sepsis

Reduced target attainment of β-lactam antibiotics is reported in critically ill patients. However, as target attainment of cefotaxime in severely ill pediatric sepsis patients may differ from adults due to age-related variation in pharmacokinetics, we aimed to assess target attainment of cefotaxime...

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Detalles Bibliográficos
Autores principales: Hartman, Stan J. F., Boeddha, Navin P., Ekinci, Ebru, Koch, Birgit C. P., Donders, Rogier, Hazelzet, Jan A., Driessen, Gertjan J., de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570664/
https://www.ncbi.nlm.nih.gov/pubmed/30968258
http://dx.doi.org/10.1007/s10096-019-03535-w