Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes

The intercellular transfer of alpha-synuclein (α-syn) has been implicated in the progression of Parkinson’s disease (PD) and multiple system atrophy (MSA). The cellular mechanisms underlying this process are now beginning to be elucidated. In this study, we demonstrate that the gap junction protein...

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Detalles Bibliográficos
Autores principales: Reyes, Juan F., Sackmann, Christopher, Hoffmann, Alana, Svenningsson, Per, Winkler, Jürgen, Ingelsson, Martin, Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570706/
https://www.ncbi.nlm.nih.gov/pubmed/30976973
http://dx.doi.org/10.1007/s00401-019-02007-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570706/
https://www.ncbi.nlm.nih.gov/pubmed/30976973
http://dx.doi.org/10.1007/s00401-019-02007-x

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