The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

The central nervous system (CNS) constitutively expresses complement (C) membrane receptors and complement proteins, including the component C5a. This is a crucial terminal effector of the C cascade, mostly involved in pain and neuroinflammatory conditions. Aberrant activation of C5a protein and its...

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Detalles Bibliográficos
Autores principales: Brandolini, Laura, Grannonico, Marta, Bianchini, Gianluca, Colanardi, Alessia, Sebastiani, Pierluigi, Paladini, Antonella, Piroli, Alba, Allegretti, Marcello, Varrassi, Giustino, Di Loreto, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570783/
https://www.ncbi.nlm.nih.gov/pubmed/30953275
http://dx.doi.org/10.1007/s12640-019-00026-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570783/
https://www.ncbi.nlm.nih.gov/pubmed/30953275
http://dx.doi.org/10.1007/s12640-019-00026-w

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