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Promoter engineering enables overproduction of foreign proteins from a single copy expression cassette in Bacillus subtilis
BACKGROUND: Bacillus subtilis is developed to be an attractive expression host to produce both secreted and cytoplasmic proteins owing to its prominent biological characteristics. Chromosomal integration is a stable expression strategy while the expression level is not ideal compared with plasmid ex...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570832/ https://www.ncbi.nlm.nih.gov/pubmed/31200722 http://dx.doi.org/10.1186/s12934-019-1159-0 |