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USP13 functions as a tumor suppressor by blocking the NF-kB-mediated PTEN downregulation in human bladder cancer

BACKGROUND: USP13 has been reported to be involved in the tumorigenesis of human cancers, however, its functional role and regulatory mechanisms in bladder cancer (BC) remain unclear. METHODS: q-RT-PCR was performed to examine the expression of miR-130b-3p, miR-301b-3p and USP13 in BC tissue samples...

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Detalles Bibliográficos
Autores principales: Man, Xiaojun, Piao, Chiyuan, Lin, Xuyong, Kong, Chuize, Cui, Xiaolu, Jiang, Yuanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570860/
https://www.ncbi.nlm.nih.gov/pubmed/31200745
http://dx.doi.org/10.1186/s13046-019-1262-4