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The effect of anti-IL-6 receptor antibody for the treatment of McH-lpr/lpr-RA1 mice that spontaneously developed destructive arthritis and enthesitis

BACKGROUND: McH-lpr/lpr-RA1 mice are a new strain of mice which spontaneously develop destructive arthritis and enthesitis in the ankle. There is no published data that drug treatment has been trialed on these mice. This study examined the effect of the mouse anti-IL-6 receptor antibody, MR16–1, for...

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Detalles Bibliográficos
Autores principales: Izumiyama, Takuya, Mori, Yu, Mori, Shiro, Mori, Naoko, Kodama, Tetsuya, Itoi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570918/
https://www.ncbi.nlm.nih.gov/pubmed/31200688
http://dx.doi.org/10.1186/s12891-019-2664-3