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DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas

BACKGROUND: Sessile serrated adenomas (SSAs) are common polyps which give rise to 20–30% of colorectal cancer (CRC). SSAs display clinicopathologic features which present challenges in surveillance, including overrepresentation in young patients, proclivity for the proximal colon and rarity of histo...

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Detalles Bibliográficos
Autores principales: Liu, Cheng, Fennell, Lochlan J., Bettington, Mark L., Walker, Neal I., Dwine, Joel, Leggett, Barbara A., Whitehall, Vicki L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570920/
https://www.ncbi.nlm.nih.gov/pubmed/31200767
http://dx.doi.org/10.1186/s13148-019-0691-4